Description

17,21-Dihydroxypregn-4-ene-3,11,20-trione 21-pivalate is a high-purity steroid derivative and a key pharmaceutical intermediate. This compound is critical for the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs) due to its specific functionalization. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development and production of corticosteroid analogs and other specialized steroid molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of corticosteroid drugs and other therapeutic steroid compounds.
• Research & Development: Used in medicinal chemistry research for exploring new steroid derivatives and their biological activities.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for steroid-based pharmaceuticals in pilot plants and commercial production.

Basic Information

Product Name	17,21-Dihydroxypregn-4-ene-3,11,20-trione 21-pivalate
CAS No.	85135-80-4
Molecular Formula	C₂₆H₃₆O₆
Molecular Weight	444.56 g/mol
Synonyms	Pregna-4-ene-3,11,20-trione, 17,21-dihydroxy-, 21-(2,2-dimethylpropanoate); 11-Oxocorticosterone 21-pivalate; 17,21-Dihydroxypregn-4-ene-3,11,20-trione 21-pivalate; 21-Pivaloyloxy-11-oxocorticosterone; 11-Dehydrocorticosterone 21-pivalate; 11-Oxocorticosterone 21-trimethylacetate; 17,21-Dihydroxy-11-oxopregn-4-ene-3,20-dione 21-pivalate
EINECS	Contact for details

Quality Control

Our 17,21-Dihydroxypregn-4-ene-3,11,20-trione 21-pivalate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.