Description

1-(4-Bromophenyl)Prop-2-Yn-1-Ol is a versatile brominated aromatic alkyne derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a bromoaryl group and a propargylic alcohol moiety, makes it a valuable building block for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as cross-coupling reactions and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring aryl-alkyne linkages.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or precursor for advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An essential substrate in Sonogashira, Suzuki, and other palladium-catalyzed coupling reactions to form carbon-carbon bonds.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags due to its reactive alkyne group for click chemistry applications.
• Academic & Industrial R&D: A fundamental reagent for methodological development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Product Name	1-(4-Bromophenyl)Prop-2-Yn-1-Ol
CAS No.	85020-75-3
Molecular Formula	C9H7BrO
Molecular Weight	211.06 g/mol
Synonyms	4-Bromophenyl propargyl alcohol; 1-(4-Bromophenyl)-2-propyn-1-ol; 4-Bromobenzeneacetylene carbinol; 4-Bromo-α-(prop-2-yn-1-yl)benzenemethanol; p-Bromophenyl propargyl alcohol; 1-(p-Bromophenyl)-2-propyn-1-ol; 4-Bromophenylpropynyl alcohol
EINECS	Contact for details

Quality Control

Our 1-(4-Bromophenyl)Prop-2-Yn-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.