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1-(Diethylamino)-3-[(2,3-Dimethoxy-6-Nitroacridin-9-Yl)Amino]Propan-2-Ol Monohydrochloride CAS NO 85006-29-7
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CAS No.:85006-29-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-(Diethylamino)-3-[(2,3-Dimethoxy-6-Nitroacridin-9-Yl)Amino]Propan-2-Ol Monohydrochloride is a specialized acridine derivative with significant biological activity, primarily utilized as a key intermediate in pharmaceutical research and development. This compound matters for its role in the synthesis of novel therapeutic agents, particularly in the fields of oncology and antimicrobial research. It is needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in the discovery of new drugs targeting DNA-interactive pathways.
Application
- Pharmaceutical Intermediate: A critical building block in the synthesis of novel acridine-based chemotherapeutic agents and antimicrobial drugs.
- Biochemical Research: Used as a research chemical in studies investigating DNA intercalation, topoisomerase inhibition, and apoptosis mechanisms.
- Anticancer Agent Development: Serves as a precursor for developing targeted cancer therapies due to its DNA-binding properties.
- Antiparasitic Drug Synthesis: Employed in the research and development of new treatments for parasitic infections.
- Fluorescent Probe Synthesis: Potential use in creating fluorescent markers for cellular imaging and diagnostic assays, leveraging the acridine chromophore.
- Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental and applied life science research.
Basic Information
| Product Name | 1-(Diethylamino)-3-[(2,3-Dimethoxy-6-Nitroacridin-9-Yl)Amino]Propan-2-Ol Monohydrochloride |
| CAS No. | 85006-29-7 |
| Molecular Formula | C22H29ClN4O5 |
| Molecular Weight | 464.94 g/mol |
| Synonyms | 9-[[2-Hydroxy-3-(diethylamino)propyl]amino]-2,3-dimethoxy-6-nitroacridine Monohydrochloride; 1-(Diethylamino)-3-[(2,3-dimethoxy-6-nitroacridin-9-yl)amino]-2-propanol Hydrochloride; 6-Nitro-2,3-dimethoxy-9-(3-diethylamino-2-hydroxypropylamino)acridine Hydrochloride; Acridine Orange derivative hydrochloride; NSC 670258 (Hydrochloride); 85006-29-7; 1-(Diethylamino)-3-[(2,3-Dimethoxy-6-Nitroacridin-9-Yl)Amino]-2-Propanol HCl |
| EINECS | Contact for details |
Quality Control
Our 1-(Diethylamino)-3-[(2,3-Dimethoxy-6-Nitroacridin-9-Yl)Amino]Propan-2-Ol Monohydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided to ensure traceability and compliance with your research or development specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | Orange to red-brown crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 2.0% |
| Residual Solvents (GC) | Complies with ICH guidelines |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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