Description

O,O'-Dibenzyl-L-Cystine Bis(Toluene-4-Sulphonate) is a protected derivative of the amino acid L-cysteine, specifically designed for advanced peptide synthesis and pharmaceutical research. This compound is crucial for researchers and manufacturers requiring precise control over cysteine reactivity and disulfide bond formation. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical industries for the development of peptide-based therapeutics and novel chemical entities.

Application

• Peptide Synthesis: Serves as a key protected intermediate for the controlled incorporation of cysteine residues into peptide chains, particularly in Solid-Phase Peptide Synthesis (SPPS).
• Pharmaceutical Intermediates: Used in the research and development of active pharmaceutical ingredients (APIs) where disulfide bridges are critical for biological activity and stability.
• Bioconjugation Chemistry: Acts as a building block for creating peptide-drug conjugates, antibody-drug conjugates (ADCs), and other targeted delivery systems.
• Chemical Biology Research: Employed in the study of protein folding, enzyme mechanisms, and the development of biochemical probes.
• Fine Chemical Manufacturing: Utilized as a specialized chiral synthon for the asymmetric synthesis of complex organic molecules.

Basic Information

Product Name	O,O'-Dibenzyl-L-Cystine Bis(Toluene-4-Sulphonate)
CAS No.	85006-27-5
Molecular Formula	C40H42N2O10S4
Molecular Weight	831.03 g/mol
Synonyms	L-Cystine, O,O'-dibenzyl-, bis(4-methylbenzenesulfonate); Dibenzyl-L-cystine bis(p-toluenesulfonate); N,N'-Dibenzyl-L-cystine bis(tosylate); O,O'-Dibenzyl-L-cystine di-p-toluenesulfonate; L-Cystine, O,O'-dibenzyl-, bis(p-toluenesulfonate); (2R,2'R)-3,3'-(Dibenzyloxy)-2,2'-diamino-4,4'-dithiadiylbis(butanoic acid) bis(4-methylbenzenesulfonate)
EINECS	Contact for details

Quality Control

Our O,O'-Dibenzyl-L-Cystine Bis(Toluene-4-Sulphonate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.