Description

(2S,3S,4R,5S)-2,3,4,5-Tetrahydroxy-6-Oxo-Hexanoic Acid is a high-purity, stereochemically defined sugar acid derivative of significant interest in advanced chemical synthesis and pharmaceutical research. Its precise chiral configuration makes it a valuable building block for the development of complex molecules, including enzyme inhibitors and carbohydrate-based therapeutics. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors seeking high-quality chiral intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel drug candidates, particularly those targeting metabolic pathways and glycosidase enzymes.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate carbohydrate metabolism and related biological processes.
• Fine Chemical Synthesis: Acts as a versatile starting material for the preparation of complex, stereochemically pure natural product analogs and specialty chemicals.
• Glycobiology Studies: Employed in research focused on carbohydrate-protein interactions, glycoconjugate synthesis, and the development of glycomimetics.
• Cosmetic & Personal Care Actives: Potential use in the development of advanced skin care ingredients due to its polyhydroxy acid structure, which may offer mild exfoliating and moisturizing properties.

Basic Information

Product Name	(2S,3S,4R,5S)-2,3,4,5-Tetrahydroxy-6-Oxo-Hexanoic Acid
CAS No.	84710-57-6
Molecular Formula	C6H10O8
Molecular Weight	210.14 g/mol
Synonyms	D-Glucaric Acid, (2S,3S,4R,5S)-Tetrahydroxy-6-oxohexanoic Acid; Saccharic Acid (D-form); D-Glucaro-1,4:6,3-dilactone (hydrolyzed form); (2S,3S,4R,5S)-2,3,4,5-Tetrahydroxyadipic Acid; L-Gularic Acid (enantiomer reference); Hexaric Acid Derivative; 6-Oxo-D-glucaric Acid
EINECS	Contact for details

Quality Control

Our (2S,3S,4R,5S)-2,3,4,5-Tetrahydroxy-6-Oxo-Hexanoic Acid is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material for GLP or GMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated or nitrogen-purged environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.