Description

(3S,4S)-Tetrahydrofuran-3,4-Diol is a high-value, chiral diol derivative of tetrahydrofuran, serving as a versatile building block in advanced organic synthesis. Its stereochemically defined structure makes it a critical intermediate for the production of complex pharmaceuticals and fine chemicals. This compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of antiviral drugs, enzyme inhibitors, and other active pharmaceutical ingredients (APIs).
• Asymmetric Catalyst Ligand Precursor: Used in the development of chiral ligands for transition metal catalysis in enantioselective reactions.
• Agrochemical Synthesis: Employed in the production of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Building Block: For constructing complex natural products, flavors, fragrances, and advanced materials.
• Polymer Chemistry: Acts as a monomer or co-monomer for creating novel polyethers and functionalized polymers with specific properties.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research.

Basic Information

Product Name	(3S,4S)-Tetrahydrofuran-3,4-Diol
CAS No.	84709-85-3
Molecular Formula	C₄H₈O₃
Molecular Weight	104.10 g/mol
Synonyms	(3S,4S)-3,4-Dihydroxytetrahydrofuran; (3S,4S)-THF-3,4-diol; (3S-cis)-Tetrahydro-3,4-furandiol; (3S,4S)-Tetrahydrofuran-3,4-diol; cis-3,4-Dihydroxytetrahydrofuran; (3S,4S)-3,4-Furandiol, tetrahydro-; L-Threitol 1,4-anhydro-
EINECS	Contact for details

Quality Control

Our (3S,4S)-Tetrahydrofuran-3,4-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.