Description

Benzene, 1-(Phenylmethoxy)-3-(2-Propyn-1-Yl)- is a specialized aromatic ether derivative containing a propargyl functional group, making it a valuable intermediate for advanced organic synthesis. This compound's unique bifunctional structure, featuring both a benzyl-protected phenol and an alkyne moiety, enables its use in constructing complex molecular architectures through coupling and cyclization reactions. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for creating libraries of compounds via click chemistry (CuAAC) and other alkyne-based coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where its aromatic-alkyne scaffold can be incorporated into bioactive molecules.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced materials with tailored properties.
• Organic Synthesis & Chemical Research: A versatile reagent for academic and industrial R&D, facilitating the construction of complex heterocycles and functionalized aromatic systems.
• Ligand & Catalyst Development: The propargyl group can be utilized to synthesize novel ligands for metal catalysis or to functionalize surfaces and nanoparticles.
• Fine Chemical Production: Intermediate in the multi-step synthesis of dyes, flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Benzene, 1-(Phenylmethoxy)-3-(2-Propyn-1-Yl)-
CAS No.	84666-34-2
Molecular Formula	C₁₆H₁₄O
Molecular Weight	222.28 g/mol
Synonyms	3-(Prop-2-yn-1-yloxy)phenyl phenylmethyl ether; 1-(Benzyloxy)-3-(prop-2-yn-1-yl)benzene; 3-(Prop-2-ynyloxy)diphenyl ether; 3-Propargyloxy diphenyl ether; m-(Benzyloxy)phenyl propargyl ether; 3-(Benzyloxy)phenyl propargyl ether; 1-(Phenylmethoxy)-3-(2-propynyl)benzene; 3-(Prop-2-yn-1-yloxy)-1-(phenylmethoxy)benzene
EINECS	Contact for details

Quality Control

Our Benzene, 1-(Phenylmethoxy)-3-(2-Propyn-1-Yl)- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and industrial use. All products undergo rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing specific test results is provided with each shipment. We adhere to cGMP principles where applicable to support our customers in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.