Description

6-Methoxy-5-(Trifluoromethyl)-1-Naphthoic Acid is a high-value, multi-functional naphthoic acid derivative distinguished by its methoxy and trifluoromethyl substituents. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a precursor for developing new-generation herbicides and pesticides, leveraging the stability imparted by the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic materials for displays and lighting due to its rigid aromatic structure.
• Organic Synthesis Building Block: Employed in coupling reactions (e.g., Suzuki, Heck) and as a carboxylic acid precursor for amide and ester formation in fine chemical production.
• Fluorinated Compound Research: Essential for studying structure-activity relationships (SAR) in medicinal chemistry, where fluorine substitution is crucial for bioavailability and metabolic stability.

Basic Information

Product Name	6-Methoxy-5-(Trifluoromethyl)-1-Naphthoic Acid
CAS No.	84532-72-9
Molecular Formula	C13H9F3O3
Molecular Weight	270.20 g/mol
Synonyms	5-(Trifluoromethyl)-6-methoxy-1-naphthoic acid; 1-Naphthalenecarboxylic acid, 6-methoxy-5-(trifluoromethyl)-; 6-Methoxy-5-trifluoromethyl-1-naphthoic acid; 6-Methoxy-5-(trifluoromethyl)naphthalene-1-carboxylic acid; 84532-72-9; 5-Trifluoromethyl-6-methoxy-1-naphthoic acid
EINECS	Contact for details

Quality Control

Our 6-Methoxy-5-(Trifluoromethyl)-1-Naphthoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.