Description

4-Iodo-n-Methylaniline Hydrochloride is a halogenated aromatic amine salt, a key building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate, enabling the introduction of both iodine and a protected aniline functionality into target molecules. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex chemical architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the iodine atom for structural diversity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck, Sonogashira) for constructing complex biaryl and conjugated systems.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized iodinated dyes and colorants.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for biochemical research and diagnostic applications.

Basic Information

Product Name	4-Iodo-n-Methylaniline Hydrochloride
CAS No.	84250-74-8
Molecular Formula	C7H9IN2·HCl
Molecular Weight	284.52 g/mol
Synonyms	N-Methyl-4-iodoaniline Hydrochloride; 4-Iodo-N-methylaniline HCl; 4-Iodo-N-methylbenzenamine hydrochloride; 1-Iodo-4-(methylamino)benzene hydrochloride; p-Iodo-N-methylaniline hydrochloride; N-Methyl-p-iodoaniline hydrochloride; 4-Iodo-N-methyl-phenylamine hydrochloride; N-Methyl-4-iodophenylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Iodo-n-Methylaniline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.