Description

2-Piperazine-4-Amino-6,7-Dimethoxy Quinoline Hydrochloride is a high-purity, specialized quinoline derivative with a piperazine substituent, offered as a hydrochloride salt for enhanced stability and handling. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Chemical Research & Development: Serves as a sophisticated building block for constructing complex heterocyclic molecules in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of new crop protection agents and pesticides.
• Ligand and Catalyst Development: The nitrogen-rich structure makes it suitable for developing novel ligands for metal catalysis.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic Research: Utilized in university and institutional labs for studying chemical reactions and biological activity of quinoline derivatives.

Basic Information

Item	Details
Product Name	2-Piperazine-4-Amino-6,7-Dimethoxy Quinoline Hydrochloride
CAS No.	84050-22-6
Molecular Formula	C₁₅H₂₁N₅O₂·HCl
Molecular Weight	339.82 g/mol
Synonyms	4-Amino-6,7-dimethoxy-2-(piperazin-1-yl)quinoline hydrochloride; 2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinoline hydrochloride; 4-Amino-6,7-dimethoxy-2-piperazin-1-ylquinoline hydrochloride; PD 153035 hydrochloride (common research alias); ZD 1839 hydrochloride (common research alias); EGFR Inhibitor (functional descriptor); Gefitinib Intermediate (related compound precursor)
EINECS	Contact for details

Quality Control

Our 2-Piperazine-4-Amino-6,7-Dimethoxy Quinoline Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.