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9H-Fluoren-9-Ylmethyl(4S)-4-Benzyl-5-Oxo-1,3-Oxazolidine-3-Carboxylate CAS NO 84000-03-3
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CAS No.:84000-03-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
9H-Fluoren-9-Ylmethyl(4S)-4-Benzyl-5-Oxo-1,3-Oxazolidine-3-Carboxylate is a specialized chiral building block and protecting group reagent widely used in advanced organic synthesis. This compound is critical for the controlled synthesis of complex molecules, particularly in the pharmaceutical sector, where stereochemical purity is paramount. It is an essential intermediate for research chemists and production facilities developing peptide-based therapeutics, active pharmaceutical ingredients (APIs), and other fine chemicals.
Application
- Pharmaceutical Intermediate: Key chiral synthon in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
- Peptide Synthesis: Serves as a crucial reagent for the introduction and protection of amino acid derivatives in solid-phase and solution-phase peptide synthesis.
- Asymmetric Synthesis: Used as a chiral auxiliary or starting material for constructing stereogenic centers with high enantiomeric excess.
- Research & Development: A valuable tool for medicinal chemistry research, process development, and exploring new synthetic methodologies in academic and industrial labs.
- Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals requiring specific stereochemistry.
- Bioconjugation Chemistry: Potential use in creating linkers or modifying biomolecules for targeted drug delivery systems.
Basic Information
| Product Name | 9H-Fluoren-9-Ylmethyl(4S)-4-Benzyl-5-Oxo-1,3-Oxazolidine-3-Carboxylate |
| CAS No. | 84000-03-3 |
| Molecular Formula | C26H21NO5 |
| Molecular Weight | 427.45 g/mol |
| Synonyms | (4S)-4-Benzyl-5-oxo-1,3-oxazolidine-3-carboxylic acid 9H-fluoren-9-ylmethyl ester; Fmoc-(S)-4-Benzyl-5-oxo-oxazolidine-3-carboxylate; (S)-4-Benzyl-5-oxooxazolidine-3-carboxylic acid 9-fluorenylmethyl ester; N-Fmoc-(S)-4-benzyl-5-oxo-oxazolidine-3-carboxylic acid; Fmoc-(S)-4-Benzyl-5-oxo-oxazolidine-3-carboxylic acid; Fmoc-(S)-4-Benzyl-5-oxo-oxazolidine-3-CO2H; Fmoc-(S)-4-Benzyl-5-oxo-oxazolidine-3-carboxylate; Fmoc-(S)-4-Benzyl-5-oxo-oxazolidine-3-carboxylic acid ester |
| EINECS | Contact for details |
Quality Control
Our 9H-Fluoren-9-Ylmethyl(4S)-4-Benzyl-5-Oxo-1,3-Oxazolidine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Conforms to reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Chiral Purity (HPLC) | ≥ 99.0% ee |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Single Impurity (HPLC) | ≤ 0.5% |
| Total Impurities (HPLC) | ≤ 2.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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