Description

(2R)-2-((Tetrahydro-2H-Pyran-2-Yl)Oxy)Propan-1-Ol is a chiral building block and protected alcohol derivative of significant value in advanced organic synthesis. Its primary importance lies in its role as a versatile intermediate for constructing complex, optically active molecules, particularly in the pharmaceutical and fine chemical industries. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where stereochemical purity is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), including antiviral, anticancer, and cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a building block for fragrances, flavors, and advanced materials requiring specific stereochemistry.
• Academic & R&D: A valuable reagent in medicinal chemistry research and process development for exploring new synthetic routes.
• Catalyst & Ligand Preparation: Can be utilized in the synthesis of chiral catalysts and ligands for asymmetric catalysis.
• Polymer Chemistry: Potential monomer or modifier for creating polymers with tailored properties.

Basic Information

Product Name	(2R)-2-((Tetrahydro-2H-Pyran-2-Yl)Oxy)Propan-1-Ol
CAS No.	83780-60-3
Molecular Formula	C8H16O3
Molecular Weight	160.21 g/mol
Synonyms	(R)-2-((Tetrahydro-2H-pyran-2-yl)oxy)-1-propanol; (R)-1-(Tetrahydro-2H-pyran-2-yloxy)propan-2-ol; (2R)-2-(Tetrahydro-2H-pyran-2-yloxy)-1-propanol; (R)-THP-Protected Glycidol; (R)-2-(Tetrahydro-2-pyranyloxy)-1-propanol; (R)-Glycidol THP ether; (R)-Oxiran-2-ylmethyl tetrahydro-2H-pyran-2-yl ether (precursor); (R)-2,3-Epoxypropyl tetrahydro-2H-pyran-2-yl ether (precursor)
EINECS	Contact for details

Quality Control

Our (2R)-2-((Tetrahydro-2H-Pyran-2-Yl)Oxy)Propan-1-Ol is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Quality is verified through comprehensive analytical techniques including HPLC, chiral GC, NMR, and optical rotation measurement. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and enantiomeric excess. We support compliance with cGMP and ISO standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Specific Rotation [α]	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.