Description

(2S)-Chroman-2-Carboxylic Acid CAS NO 83780-46-5 is a high-purity chiral building block and key intermediate in organic synthesis. This compound matters for its role in constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and advanced materials. It is needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in cardiovascular and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry influences biological activity.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new chiral catalysts for stereoselective reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require enantiomerically pure components.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs at universities and corporate labs.

Basic Information

Product Name	(2S)-Chroman-2-Carboxylic Acid
CAS No.	83780-46-5
Molecular Formula	C10H10O3
Molecular Weight	178.18 g/mol
Synonyms	(S)-Chroman-2-carboxylic acid; (2S)-3,4-Dihydro-2H-1-benzopyran-2-carboxylic acid; (S)-3,4-Dihydro-2H-chromene-2-carboxylic acid; (S)-2-Carboxychroman; (S)-2,3-Dihydro-1-benzopyran-2-carboxylic acid; L-Chroman-2-carboxylic acid; (S)-Dihydrocoumarin-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our (2S)-Chroman-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with high-purity standards for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.