Description

4(3H)-Quinazolinone, 2-(4-(3-((2-(3,4-Dimethoxyphenyl)Ethyl)Methylamino)-2-Hydroxypropoxy)Phenyl)-6-Methoxy-3-Methyl-, Dihydrochloride is a high-purity, complex organic compound belonging to the quinazolinone class, which is of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or reference standard for the development of novel therapeutic agents, particularly in areas targeting specific enzymatic pathways. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates with targeted biological activity.
• Biochemical Research: Used as a reference standard or tool compound in enzyme inhibition studies and receptor binding assays.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Active Pharmaceutical Ingredient (API) Development: Investigated for use in the development of new APIs for various therapeutic areas.
• Contract Manufacturing: Supplied to CROs and CDMOs for custom synthesis projects and process development.
• Analytical Standard: Provides a high-purity standard for method development and quality control in analytical laboratories.

Basic Information

Product Name	4(3H)-Quinazolinone, 2-(4-(3-((2-(3,4-Dimethoxyphenyl)Ethyl)Methylamino)-2-Hydroxypropoxy)Phenyl)-6-Methoxy-3-Methyl-, Dihydrochloride
CAS No.	83722-15-0
Molecular Formula	C30H35N3O6 • 2HCl
Molecular Weight	606.54 g/mol (free base: 533.62 g/mol)
Synonyms	2-[4-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]-2-hydroxypropoxy]phenyl]-6-methoxy-3-methyl-4(3H)-quinazolinone dihydrochloride; Quinazolinone derivative 83722-15-0; 2-(4-(3-((2-(3,4-Dimethoxyphenyl)Ethyl)Methylamino)-2-Hydroxypropoxy)Phenyl)-6-Methoxy-3-Methyl-4(3H)-Quinazolinone Dihydrochloride; L-654,066 (potential research code); L654066; A complex quinazolinone β-adrenergic blocker analog.
EINECS	Contact for details

Quality Control

Every batch of our 4(3H)-Quinazolinone derivative is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment aligns with the standards expected for pharmaceutical research materials, ensuring reliability for your critical development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.