Description

(+/-)-2-[4-(Trans)-((1'R,2'S)-2'-Hydroxycyclopentylmethyl)-Phenyl]Propionic Acid is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters for its role as a key building block in the development of enantiomerically pure active pharmaceutical ingredients (APIs), where precise stereochemistry is critical for therapeutic efficacy. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for the production of novel anti-inflammatory and analgesic drug candidates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key precursor in multi-step synthetic routes for producing enantiomerically pure final APIs.
• Asymmetric Synthesis Research: Used in academic and industrial research to study and develop new stereoselective catalytic reactions and methodologies.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Process Chemistry Development: Utilized in scale-up and optimization studies for the commercial manufacturing of complex organic molecules.

Basic Information

Product Name	(+/-)-2-[4-(Trans)-((1'R,2'S)-2'-Hydroxycyclopentylmethyl)-Phenyl]Propionic Acid
CAS No.	83599-40-0
Molecular Formula	C16H22O3
Molecular Weight	262.34 g/mol
Synonyms	2-[4-[(1R,2S)-2-Hydroxycyclopentylmethyl]phenyl]propanoic acid; α-Methyl-4-[(1R,2S)-2-hydroxycyclopentylmethyl]benzeneacetic acid; (RS)-2-(4-{[(1R,2S)-2-Hydroxycyclopentyl]methyl}phenyl)propanoic Acid; trans-2-Hydroxycyclopentylmethyl Phenylpropionic Acid Derivative; Arylpropionic Acid Derivative; Chiral Cyclopentyl Phenylpropionic Acid; Pharmaceutical Intermediate 83599-40-0
EINECS	Contact for details

Quality Control

Our (+/-)-2-[4-(Trans)-((1'R,2'S)-2'-Hydroxycyclopentylmethyl)-Phenyl]Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and impurity profile analysis by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (sum of enantiomers)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.