Description

7-Hydroxymethylbenz(A)Anthracene-3,4-Dihydrodiol is a high-purity, polycyclic aromatic hydrocarbon (PAH) derivative of significant interest in advanced chemical research and development. This compound is a critical intermediate and reference standard for studying metabolic activation pathways and DNA adduct formation related to benz(a)anthracene, a model environmental carcinogen. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories engaged in toxicology studies, metabolic profiling, and the synthesis of labeled compounds for biomarker analysis.

Application

• Biochemical Research: Serves as a key intermediate in the study of PAH metabolism and carcinogenesis mechanisms.
• Analytical Reference Standard: Used for calibration and quantification in high-performance liquid chromatography (HPLC) and mass spectrometry (MS) for toxicological analysis.
• Metabolite Synthesis: Acts as a precursor in the synthesis of diol-epoxide metabolites for DNA binding and mutagenicity studies.
• Environmental Toxicology: Employed in assays to understand the biological impact and metabolic fate of benz(a)anthracene derivatives in environmental samples.
• Pharmaceutical Development: Used in early-stage research for investigating drug metabolism and potential toxicological pathways of new chemical entities.

Basic Information

Product Name	7-Hydroxymethylbenz(A)Anthracene-3,4-Dihydrodiol
CAS No.	83481-43-0
Molecular Formula	C21H16O3
Molecular Weight	316.35 g/mol
Synonyms	7-(Hydroxymethyl)benz[a]anthracene-3,4-diol; 7-Hydroxymethyl-BA-3,4-dihydrodiol; 3,4-Dihydro-3,4-dihydroxy-7-(hydroxymethyl)benz[a]anthracene; BA 7-HM-3,4-diol; Benz(a)anthracene-7-hydroxymethyl-3,4-dihydrodiol; 7-HMBA-3,4-dihydrodiol
EINECS	Contact for details

Quality Control

Our 7-Hydroxymethylbenz(A)Anthracene-3,4-Dihydrodiol is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods, including HPLC and NMR, are validated to provide reliable data for critical research.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated place away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to pale yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	≤ 5.0% total
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.