Description

(1R)-2,3,4,4Aα,8,8Aβ-Hexahydro-6-Hydroxymethyl-4α-Isopropylspiro[Naphthalene-1(7H),2'-Oxiran]-7-One CAS NO 83474-53-7 is a high-purity, complex spirocyclic compound featuring a fused naphthalene-oxirane structure with hydroxymethyl and isopropyl functional groups. This compound matters as a sophisticated chiral building block and intermediate, enabling the synthesis of novel molecules with precise stereochemistry for advanced research and development. It is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers focused on creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for complex small-molecule drugs.
• Agrochemical Synthesis: Used in the creation of novel, high-efficacy pesticides and herbicides where its specific stereochemistry is critical for biological activity.
• Advanced Material Research: Acts as a precursor for specialty polymers, liquid crystals, or other functional materials requiring complex, rigid molecular frameworks.
• Asymmetric Catalysis: Employed as a ligand or a substrate in the development and study of new asymmetric catalytic reactions.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic synthesis, total synthesis projects, and exploring new chemical spaces.
• Flavor & Fragrance Industry: Potential use as an intermediate for synthesizing unique, high-value aroma chemicals with complex structural motifs.

Basic Information

Product Name	(1R)-2,3,4,4Aα,8,8Aβ-Hexahydro-6-Hydroxymethyl-4α-Isopropylspiro[Naphthalene-1(7H),2'-Oxiran]-7-One
CAS No.	83474-53-7
Molecular Formula	C₁₆H₂₂O₃
Molecular Weight	262.34 g/mol
Synonyms	(1R)-6-(Hydroxymethyl)-4α-(1-methylethyl)spiro[1,7-dihydronaphthalene-1,2'-oxirane]-7-one; (1R)-4α-Isopropyl-6-hydroxymethylspiro[1,7-dihydronaphthalene-1,2'-oxirane]-7-one; Spiro[naphthalene-1(7H),2'-oxiran]-7-one, 2,3,4,4a,8,8a-hexahydro-6-(hydroxymethyl)-4a-(1-methylethyl)-, (1R,4aR,8aS)-; (1R,4aR,8aS)-Hexahydro-6-(hydroxymethyl)-4a-(1-methylethyl)spiro[naphthalene-1(7H),2'-oxiran]-7-one; CAS 83474-53-7
EINECS	Contact for details

Quality Control

Our (1R)-2,3,4,4Aα,8,8Aβ-Hexahydro-6-Hydroxymethyl-4α-Isopropylspiro[Naphthalene-1(7H),2'-Oxiran]-7-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.