Description

Acetyl-D-2-Thienylalanine is a high-purity, non-natural amino acid derivative featuring a thienyl side chain. This compound is a critical chiral building block in pharmaceutical research and development, valued for its role in modulating peptide structure and biological activity. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis of novel therapeutic agents and bioactive peptides.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for metabolic and neurological disorders.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a unique, sulfur-containing aromatic moiety into peptide sequences.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of selective enzyme inhibitors.
• Chemical Biology Research: Employed as a tool compound for studying protein-protein interactions and enzyme mechanisms due to its modified side chain.
• Asymmetric Synthesis: Acts as a valuable starting material or auxiliary in catalytic asymmetric transformations to create complex chiral molecules.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Acetyl-D-2-Thienylalanine
CAS No.	83396-77-4
Molecular Formula	C9H11NO3S
Molecular Weight	213.25 g/mol
Synonyms	N-Acetyl-D-2-thienylalanine; (R)-2-Acetamido-3-(thiophen-2-yl)propanoic acid; D-2-Thienylalanine, N-acetyl-; Ac-D-2-Thienylalanine; N-Acetyl-3-(2-thienyl)-D-alanine; N-Acetyl-D-β-(2-thienyl)alanine; Ac-D-ThiAla-OH; N-Acetyl-D-2-thienylalanine
EINECS	Contact for details

Quality Control

Our Acetyl-D-2-Thienylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (D-isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.