Description

2-Chloro-n-Methylquinazolin-4-Amine is a high-purity, synthetically versatile quinazoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized scaffold essential for constructing complex molecules with targeted biological or material properties. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other therapeutic pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the bioactive quinazoline core.
• Organic Synthesis Building Block: Employed in medicinal and combinatorial chemistry for constructing diverse heterocyclic libraries for screening.
• Material Science Research: Investigated as a precursor for organic electronic materials or metal-organic frameworks (MOFs) due to its nitrogen-rich structure.
• Biochemical Tool Compound: Utilized in life science research to study biological mechanisms and enzyme interactions.

Basic Information

Product Name	2-Chloro-n-Methylquinazolin-4-Amine
CAS No.	83260-68-8
Molecular Formula	C9H8ClN3
Molecular Weight	193.63 g/mol
Synonyms	2-Chloro-N-methylquinazolin-4-amine; 4-Amino-2-chloro-N-methylquinazoline; 2-Chloro-4-(methylamino)quinazoline; N-Methyl-2-chloroquinazolin-4-amine; 83260-68-8; 2-Chloro-N-methyl-4-quinazolinamine; 4-Quinazolinamine, 2-chloro-N-methyl-
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-Methylquinazolin-4-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. Certificates of Analysis (COA) detailing all quality parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.