Description

Methyl-3-Phenylbicyclo[1.1.1]Pentane-1-Carboxylate is a high-value, synthetically versatile bicyclic compound featuring a unique [1.1.1]propellane core structure. This compound serves as a critical advanced pharmaceutical intermediate (API) and a sophisticated building block in medicinal chemistry and organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Building Block: Used to introduce the rigid, three-dimensional bicyclo[1.1.1]pentane scaffold as a bioisostere for tert-butyl or phenyl groups to improve drug potency and metabolic stability.
• Agrochemical Research: Serves as a structural component in the development of new-generation pesticides and herbicides with enhanced activity.
• Material Science: Potential monomer or cross-linker for creating polymers with unique thermal and mechanical properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and other catalytic transformations to create complex, strained organic molecules for academic and industrial research.

Basic Information

Product Name	Methyl-3-Phenylbicyclo[1.1.1]Pentane-1-Carboxylate
CAS No.	83249-09-6
Molecular Formula	C13H14O2
Molecular Weight	202.25 g/mol
Synonyms	Methyl 3-phenylbicyclo[1.1.1]pentane-1-carboxylate; 3-Phenylbicyclo[1.1.1]pentane-1-carboxylic acid methyl ester; Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-phenyl-, methyl ester; Methyl 3-phenyl[1.1.1]propellane-1-carboxylate; 83249-09-6; 1-Carbomethoxy-3-phenylbicyclo[1.1.1]pentane
EINECS	Contact for details

Quality Control

Our Methyl-3-Phenylbicyclo[1.1.1]Pentane-1-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.