Description

1-(2-Hydroxyethyl)Cyclobutanol is a versatile bifunctional organic compound featuring both a cyclobutanol and a hydroxyethyl group, making it a valuable building block in synthetic chemistry. Its unique structure provides a rigid cyclobutane ring for conformational control while offering two hydroxyl sites for selective functionalization, enabling the synthesis of complex molecular architectures. This compound is particularly relevant for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop novel active ingredients or advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon or scaffold in the research and development of new therapeutic agents, including central nervous system (CNS) drugs and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, where the cyclobutane ring can enhance biological activity and environmental stability.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for creating specialty polymers, coatings, and resins with tailored thermal and mechanical properties.
• Ligand & Catalyst Development: Employed in the synthesis of novel chelating ligands and organocatalysts for asymmetric synthesis and transition metal catalysis.
• Fragrance & Flavor Chemistry: Utilized as a precursor for synthesizing unique aroma chemicals and flavoring substances with complex olfactory profiles.
• Organic Synthesis Building Block: A fundamental starting material for constructing complex natural product analogs and other high-value fine chemicals through ring-opening, esterification, or etherification reactions.

Basic Information

Product Name	1-(2-Hydroxyethyl)Cyclobutanol
CAS No.	83237-27-8
Molecular Formula	C6H12O2
Molecular Weight	116.16 g/mol
Synonyms	2-(1-Hydroxycyclobutyl)ethanol; Cyclobutanol, 1-(2-hydroxyethyl)-; 1-(2-Hydroxyethyl)cyclobutanol; 2-(Hydroxycyclobutyl)ethanol; (1-Hydroxycyclobutyl)ethanol; β-Hydroxyethylcyclobutanol; Cyclobutyl ethanol derivative
EINECS	Contact for details

Quality Control

Our 1-(2-Hydroxyethyl)Cyclobutanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.