Description

8-Chloro-3,4-Dihydroquinolin-2(1H)-One is a versatile heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique quinolinone core structure, functionalized with a chlorine atom, makes it a valuable intermediate for creating complex molecules with targeted biological or material properties. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) agents, antimicrobials, and kinase inhibitors.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the chlorinated quinolinone moiety can contribute to biological activity.
• Material Science Research: Serves as a precursor for the synthesis of organic electronic materials, ligands for metal complexes, and specialty polymers.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, structure-activity relationship (SAR) studies, and library synthesis for high-throughput screening.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex fine chemicals and specialty dyes.

Basic Information

Product Name	8-Chloro-3,4-Dihydroquinolin-2(1H)-One
CAS No.	83229-23-6
Molecular Formula	C9H8ClNO
Molecular Weight	181.62 g/mol
Synonyms	8-Chloro-1,2,3,4-tetrahydroquinolin-2-one; 8-Chloro-3,4-dihydro-2(1H)-quinolinone; 8-Chloro-2-oxo-1,2,3,4-tetrahydroquinoline; 8-Chlorotetrahydro-2-quinolone; 2(1H)-Quinolinone, 8-chloro-3,4-dihydro-
EINECS	Contact for details

Quality Control

Our 8-Chloro-3,4-Dihydroquinolin-2(1H)-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.