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Dibenz(A,H)Anthracene-1,2,3,4-Tetrahydro-3,4-Diol CAS NO 83197-99-3


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CAS No.:83197-99-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dibenz(A,H)Anthracene-1,2,3,4-Tetrahydro-3,4-Diol is a high-purity, polycyclic aromatic hydrocarbon (PAH) derivative of significant interest in advanced chemical research and development. This compound serves as a critical intermediate and reference standard for toxicological and metabolic studies of PAHs, which are important environmental contaminants. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical developers focused on environmental health, carcinogenicity research, and analytical method validation.

Application

  • Analytical Reference Standard: Used as a certified standard in gas chromatography (GC) and high-performance liquid chromatography (HPLC) for the quantification and identification of PAH metabolites in complex matrices.
  • Toxicology Research: Serves as a key metabolite in studies investigating the metabolic activation, DNA adduct formation, and carcinogenic pathways of Dibenz(a,h)anthracene.
  • Environmental Monitoring: Employed in method development and quality control for analyzing PAH contamination in soil, water, and air samples to assess environmental and human health risks.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to cytochrome P450 and epoxide hydrolase activities involved in PAH metabolism.
  • Pharmaceutical Development: Acts as a crucial intermediate in the synthesis of more complex molecules for pharmacological investigation and as a tool compound in assay development.

Basic Information

Product Name Dibenz(A,H)Anthracene-1,2,3,4-Tetrahydro-3,4-Diol
CAS No. 83197-99-3
Molecular Formula C22H18O2
Molecular Weight 314.38 g/mol
Synonyms 1,2,3,4-Tetrahydrodibenz[a,h]anthracene-3,4-diol; 3,4-Dihydroxy-1,2,3,4-tetrahydrodibenz[a,h]anthracene; DB[a,h]A-3,4-diol; Dibenzo[a,h]anthracene 3,4-dihydrodiol; Anti-DB[a,h]A-3,4-dihydrodiol; PAH Metabolite Standard
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Quality Control

Our Dibenz(A,H)Anthracene-1,2,3,4-Tetrahydro-3,4-Diol is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, essential for reliable research outcomes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for reference materials, and our quality system supports traceability for analytical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, keep the container in a freezer. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Solubility Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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