Description

4-Chloro-[1,5]Naphthyridine-3-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for its versatile reactivity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, antiviral agents, and other biologically active molecules targeting the naphthyridine scaffold.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce the functionalized naphthyridine moiety into more complex systems.
• Material Science Research: Investigated as a precursor for the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), or fluorescent materials due to its conjugated structure.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in regulatory and research laboratories.

Basic Information

Product Name	4-Chloro-[1,5]Naphthyridine-3-Carboxylic Acid Ethyl Ester
CAS No.	83067-95-2
Molecular Formula	C11H9ClN2O2
Molecular Weight	236.66 g/mol
Synonyms	Ethyl 4-Chloro-1,5-naphthyridine-3-carboxylate; 4-Chloro-1,5-naphthyridine-3-carboxylic acid ethyl ester; 83067-95-2; 4-Chloro-1,5-naphthyridine-3-carboxylic acid, ethyl ester; Ethyl 4-chloro[1,5]naphthyridine-3-carboxylate; 1,5-Naphthyridine, 4-chloro-3-(ethoxycarbonyl)-; 4-Chloro-3-ethoxycarbonyl-1,5-naphthyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-[1,5]Naphthyridine-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.