Description

Alpha,2-Pyridyl-2,8-Bis(Trifluoromethyl)Quinoline-4-Acetonitrile is a high-value, multi-functional heterocyclic compound featuring a quinoline core substituted with pyridyl, trifluoromethyl, and acetonitrile groups. This unique molecular architecture makes it a critical advanced intermediate for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the development of new drug candidates, especially in areas targeting neurological disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the biological activity of the quinoline and pyridine motifs.
• Material Science Research: Serves as a precursor for creating specialized organic ligands and functional molecules used in catalysis and electronic materials.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to the pharmaceutical industry.

Basic Information

Product Name	Alpha,2-Pyridyl-2,8-Bis(Trifluoromethyl)Quinoline-4-Acetonitrile
CAS No.	83012-12-8
Molecular Formula	C₂₀H₉F₆N₃
Molecular Weight	405.31 g/mol
Synonyms	2-(2-Pyridinyl)-2,8-bis(trifluoromethyl)-4-quinolineacetonitrile; 4-Quinolineacetonitrile, α-(2-pyridinyl)-2,8-bis(trifluoromethyl)-; α-(2-Pyridyl)-2,8-bis(trifluoromethyl)-4-quinolineacetonitrile; 2,8-Bis(trifluoromethyl)-α-(2-pyridinyl)-4-quinolineacetonitrile; 83012-12-8; α-(2-Pyridyl)-2,8-Bis(Trifluoromethyl)Quinoline-4-Acetonitrile
EINECS	Contact for details

Quality Control

Our production of Alpha,2-Pyridyl-2,8-Bis(Trifluoromethyl)Quinoline-4-Acetonitrile adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.