Description

2,8-Bis(Trifluoromethyl)-4-Quinolyl(1-Oxypyrid-2-Yl) Methane is a specialized fluorinated heterocyclic compound that serves as a high-value building block in advanced organic synthesis. Its unique molecular architecture, featuring both quinoline and pyridine N-oxide moieties with trifluoromethyl groups, makes it a critical intermediate for developing novel materials with tailored electronic and chemical properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in catalysis, ligand design, and the creation of functional fluorophores.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents, where the fluorine atoms enhance metabolic stability and bioavailability.
• Agrochemical Research: Used in developing next-generation pesticides and herbicides, where the trifluoromethyl groups contribute to improved lipophilicity and environmental persistence of active ingredients.
• Catalyst & Ligand Synthesis: Serves as a sophisticated scaffold for constructing nitrogen-containing ligands used in transition metal catalysis for fine chemical and polymer production.
• Advanced Material Development: Employed in the research of organic semiconductors, non-linear optical (NLO) materials, and specialty dyes due to its electron-deficient aromatic system and potential for charge transport.
• Chemical Biology Probe: Utilized as a core structure for creating fluorescent probes and molecular tags to study biological processes and protein interactions.

Basic Information

Product Name	2,8-Bis(Trifluoromethyl)-4-Quinolyl(1-Oxypyrid-2-Yl) Methane
CAS No.	83012-10-6
Molecular Formula	C₁₈H₁₀F₆N₂O
Molecular Weight	384.28 g/mol
Synonyms	2,8-Bis(trifluoromethyl)-4-[(1-oxidopyridin-2-yl)methyl]quinoline; 2,8-Bis(trifluoromethyl)-4-(1-oxopyridin-2-ylmethyl)quinoline; 4-[(1-Oxido-2-pyridinyl)methyl]-2,8-bis(trifluoromethyl)quinoline; 2,8-Bis(trifluoromethyl)-4-(pyridine-1-oxide-2-ylmethyl)quinoline; 83012-10-6; 4-(1-Oxidopyridin-2-ylmethyl)-2,8-bis(trifluoromethyl)quinoline
EINECS	Contact for details

Quality Control

Our production of 2,8-Bis(Trifluoromethyl)-4-Quinolyl(1-Oxypyrid-2-Yl) Methane adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.