Description

Fmoc-Obt CAS NO 82911-71-5 is a specialized amino acid derivative widely used as a key coupling reagent in solid-phase peptide synthesis (SPPS). Its primary value lies in its role as an active ester, facilitating efficient and high-yielding amide bond formation with minimal racemization, which is critical for producing pure, complex peptides. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors engaged in the development of peptide-based therapeutics, diagnostics, and research reagents.

Application

• Key reagent in solid-phase peptide synthesis (SPPS) for the incorporation of Fmoc-protected amino acids.
• Facilitates the synthesis of complex and long-chain peptides for pharmaceutical research and drug discovery.
• Used in the production of peptide antigens for antibody generation and immunological studies.
• Essential for creating custom peptides used in biochemical assays and as research tools.
• Applied in the development of peptide hormones and other bioactive peptide molecules.
• Supports process development in GMP manufacturing of peptide active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Fmoc-Obt
CAS No.	82911-71-5
Molecular Formula	C24H18N2O5
Molecular Weight	414.41 g/mol
Synonyms	Fmoc-OBt; N-[(9H-Fluoren-9-ylmethoxy)carbonyloxy]benzotriazole; 1-[(9-Fluorenylmethyloxycarbonyl)oxy]benzotriazole; Fmoc-Oxybenzotriazole; O-(Fluoren-9-ylmethoxycarbonyl)benzotriazole; Fmoc benzotriazolyl carbonate; Fmoc-OBt ester; Benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate (Common reagent association)
EINECS	Contact for details

Quality Control

Our Fmoc-Obt is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive synthetic applications. Each lot is analyzed using advanced techniques like HPLC and NMR to confirm identity and purity, meeting the stringent requirements of pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all quality parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.