Description

Fluoranthene trans-2,3-Dihydrodiol is a specific dihydrodiol metabolite of the polycyclic aromatic hydrocarbon (PAH) fluoranthene. This compound is of significant value as a key intermediate and reference standard in environmental toxicology and metabolic pathway research. It is primarily required by analytical laboratories, research institutions, and chemical manufacturers focused on PAH biodegradation studies, metabolic profiling, and the synthesis of advanced metabolites for calibration and method development.

Application

• Metabolic Research Standard: Used as a certified reference material (CRM) for studying the metabolic activation and detoxification pathways of fluoranthene in biological systems.
• Environmental Analysis: Serves as a critical analytical standard in HPLC, GC-MS, or LC-MS methods for quantifying PAH metabolites in environmental samples (e.g., soil, water, biological tissues).
• Toxicology Studies: Employed in in vitro and in vivo assays to investigate the genotoxicity and carcinogenicity of fluoranthene diol metabolites.
• Biodegradation Monitoring: Acts as a marker compound to monitor the progress of microbial degradation of fluoranthene in bioremediation projects.
• Chemical Synthesis Intermediate: Utilized as a building block for the synthesis of further downstream metabolites, such as diol-epoxides, which are ultimate carcinogens.
• Enzyme Activity Assays: Applied in studies to assess the activity of enzymes like cytochrome P450 and epoxide hydrolase involved in PAH metabolism.

Basic Information

Product Name	Fluoranthene trans-2,3-Dihydrodiol
CAS No.	82911-12-4
Molecular Formula	C₁₆H₁₂O₂
Molecular Weight	236.26 g/mol
Synonyms	trans-2,3-Dihydroxy-2,3-dihydrofluoranthene; 2,3-Dihydrofluoranthene-2,3-diol; Fluoranthene 2,3-dihydrodiol; 2,3-Dihydro-2,3-dihydroxyfluoranthene; Benzo[jk]fluorene-2,3-diol, 1,2,3,10b-tetrahydro-; PAH Metabolite (Fluoranthene); Fluoranthene-2,3-diol
EINECS	Contact for details

Quality Control

Every batch of Fluoranthene trans-2,3-Dihydrodiol is produced and analyzed under strict quality protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) providing detailed results for purity (HPLC), identity (IR, NMR), and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	≤ 5.0% total
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.