Description

1,2,3,5,6,7-Hexahydro-N,Alpha,α-Trimethyl-S-Indacene-4-Ethanamine Hydrochloride is a high-purity organic compound, specifically a hydrochlorinated amine derivative of a hexahydroindacene structure, serving as a critical advanced intermediate in pharmaceutical synthesis. Its value lies in enabling the development of complex active pharmaceutical ingredients (APIs) and other fine chemicals requiring a specific, functionalized polycyclic framework. This product is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require complex amine functionalities.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor or dopant material in the development of electron-transport or host materials for OLED displays and lighting.
• Ligand Synthesis for Catalysis: Utilized to create sophisticated chiral or polycyclic ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry, including cyclization and functionalization reactions.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other performance chemicals where its unique polycyclic structure imparts specific properties.

Basic Information

Product Name	1,2,3,5,6,7-Hexahydro-N,Alpha,α-Trimethyl-S-Indacene-4-Ethanamine Hydrochloride
CAS No.	82875-69-2
Molecular Formula	C18H28ClN
Molecular Weight	293.88 g/mol
Synonyms	4-(2-Amino-2-methylpropyl)-1,2,3,5,6,7-hexahydro-s-indacene hydrochloride; N,α,α-Trimethyl-1,2,3,5,6,7-hexahydro-s-indacene-4-ethanamine hydrochloride; 1,2,3,5,6,7-Hexahydro-4-(2-methyl-2-aminopropyl)indene hydrochloride; Trimethylhexahydroindaceneethanamine HCl; s-Indacene-4-ethanamine, 1,2,3,5,6,7-hexahydro-N,α,α-trimethyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our 1,2,3,5,6,7-Hexahydro-N,Alpha,α-Trimethyl-S-Indacene-4-Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.