Description

Poly((2-9)-α-n-Acetylneuraminic Acid) is a high-purity, polymeric form of N-acetylneuraminic acid, a critical sialic acid derivative. This compound is essential for advanced research and development in glycobiology and pharmaceutical sciences, offering a stable, high-molecular-weight alternative to monomeric forms. It is primarily utilized by research institutions, diagnostic manufacturers, and biopharmaceutical companies developing novel therapeutics, vaccines, and diagnostic tools that target sialic acid-mediated biological processes.

Application

• Glycobiology Research: Used as a standard or substrate for studying sialidase (neuraminidase) enzyme activity, sialic acid metabolism, and glycan biosynthesis pathways.
• Pharmaceutical Development: Serves as a key intermediate or starting material in the synthesis of neuraminidase inhibitors and other sialic acid-based therapeutic agents.
• Diagnostic Reagents: Incorporated into enzymatic assay kits for the detection and quantification of neuraminidase activity, relevant for influenza research and virology.
• Vaccine Adjuvant Research: Investigated for its immunomodulatory properties and potential use in conjugate vaccine formulations to enhance immune response.
• Biomimetic Materials: Utilized in the development of biocompatible coatings and materials that mimic cell surface glycocalyx for tissue engineering and drug delivery systems.
• Reference Standard: Acts as a certified reference material (CRM) for quality control in the production of sialic acid-related pharmaceuticals and biologics.

Basic Information

Product Name	Poly((2-9)-α-n-Acetylneuraminic Acid)
CAS No.	82803-97-2
Molecular Formula	(C11H19NO9)n
Molecular Weight	Variable (Polymeric)
Synonyms	Poly(α-N-acetylneuraminic acid); Poly(NANA); Polymeric Sialic Acid; Poly(Neu5Ac); Polysialic Acid (α-2,9 linked); Colominic Acid (related polymer); Poly(2-9)-α-N-Acetylneuraminic Acid; Oligo/poly-Sia
EINECS	Contact for details

Quality Control

Our Poly((2-9)-α-n-Acetylneuraminic Acid) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and polymer length distribution, NMR for structural confirmation, and specific enzymatic activity assays. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95% (as polymeric sialic acid)
Degree of Polymerization (n)	2 - 9 (Specify range available)
Water Content (KF)	≤ 5.0 %
Specific Rotation	Contact for details
Bacterial Endotoxins	< 10.0 EU/mg (if applicable)
Microbial Enumeration	Meets standard bioburden limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.