Description

5-Methoxy-3,4-Dihydro-1,7-Naphthyridin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the naphthyridine class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Serves as a structural motif for developing new herbicides, fungicides, or insecticides with specific biological activity.
• Chemical Research & Development: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Active Pharmaceutical Ingredient (API) Manufacturing: Incorporated into the final chemical structure of APIs under current Good Manufacturing Practice (cGMP) conditions.
• Contract Research Organizations (CROs): Supplied to CROs for client-sponsored drug discovery and process development projects.

Basic Information

Product Name	5-Methoxy-3,4-Dihydro-1,7-Naphthyridin-2(1H)-One
CAS No.	82673-70-9
Molecular Formula	C9H10N2O2
Molecular Weight	178.19 g/mol
Synonyms	5-Methoxy-1,2,3,4-tetrahydro-1,7-naphthyridin-2-one; 5-Methoxy-3,4-dihydro-2H-1,7-naphthyridin-2-one; 2H-1,7-Naphthyridin-2-one, 3,4-dihydro-5-methoxy-; 82673-70-9; 5-Methoxy-1,7-naphthyridin-2(1H)-one, 3,4-dihydro-
EINECS	Contact for details

Quality Control

Our 5-Methoxy-3,4-Dihydro-1,7-Naphthyridin-2(1H)-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.