Description

3-(2,4-Dioxo-1,4-Dihydroquinazolin-3(2H)-Yl)-Propanoic Acid is a high-purity, functionalized quinazoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the development of novel molecules with targeted biological and material properties. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging the quinazoline core for biological activity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in display and lighting technologies.
• Ligand and Catalyst Development: Employed in the synthesis of complex ligands for metal-organic frameworks (MOFs) or asymmetric catalysis.
• Bioconjugation and Probe Synthesis: The carboxylic acid functionality allows for coupling to biomolecules, useful in diagnostic and imaging agent development.
• Academic and Industrial R&D: A valuable reagent for methodological studies and exploring new chemical spaces in synthetic chemistry.

Basic Information

Product Name	3-(2,4-Dioxo-1,4-Dihydroquinazolin-3(2H)-Yl)-Propanoic Acid
CAS No.	82603-63-2
Molecular Formula	C₁₁H₁₀N₂O₄
Molecular Weight	234.21 g/mol
Synonyms	3-(2,4-Dioxo-1,4-dihydro-3H-quinazolin-3-yl)propanoic acid; 3-(2,4-Dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)propanoic acid; 3-(3,4-Dihydro-2,4-dioxo-1H-quinazolin-3-yl)propanoic acid; 3-(2,4-Dioxo-3,4-dihydro-1H-quinazolin-3-yl)propanoic acid; NSC 339586; Quinazoline-3-propanoic acid derivative; 82603-63-2 (CAS)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, residual solvents, and related substances are available upon request. We adhere to a cGMP-compliant quality management system, ensuring traceability and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.