Description

(R)-(+)-1-(1-Naphthyl)Ethylamine Hydrochloride is a high-purity chiral amine salt, widely recognized as a versatile chiral resolving agent and a critical building block in asymmetric synthesis. Its primary value lies in its ability to separate enantiomers of carboxylic acids and other racemic compounds, making it indispensable for producing optically pure pharmaceuticals and fine chemicals. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high enantiomeric purity and reliable performance in chiral separations and syntheses.

Application

• Chiral Resolution Agent: Widely used for the optical resolution of racemic carboxylic acids and other acidic compounds via diastereomeric salt formation.
• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific (R)-configuration.
• Asymmetric Synthesis Catalyst/ Ligand Precursor: Utilized in the preparation of chiral ligands for metal-catalyzed asymmetric reactions.
• Analytical Chemistry: Employed as a chiral selector or derivatizing agent in chromatographic methods like HPLC for enantiomeric purity analysis.
• Agrochemical Research: Used in the development of chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Fine Chemical Synthesis: Applied in the production of specialty chemicals, flavors, and fragrances that demand high enantiopurity.

Basic Information

Product Name	(R)-(+)-1-(1-Naphthyl)Ethylamine Hydrochloride
CAS No.	82572-04-1
Molecular Formula	C₁₂H₁₃N·HCl
Molecular Weight	207.70 g/mol (Free base: 171.24 g/mol)
Synonyms	(R)-(+)-1-(1-Naphthyl)ethylamine HCl; (R)-1-(1-Naphthyl)ethylammonium chloride; (R)-1-(Naphthalen-1-yl)ethan-1-amine hydrochloride; (R)-1-(α-Naphthyl)ethylamine hydrochloride; (R)-NEA HCl; (R)-N-(1-Naphthyl)ethylamine hydrochloride; D-NEA HCl; (R)-Methyl-1-naphthylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-(+)-1-(1-Naphthyl)Ethylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets stringent specifications for use in sensitive applications like pharmaceutical synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee consistent quality, high enantiomeric excess (ee), and batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (ee)	≥99.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.