Description

12-N,n-Diacetylaminobenzo(A)Pyrene is a high-purity, synthetic polycyclic aromatic hydrocarbon (PAH) derivative, specifically designed for advanced research and analytical applications. This compound serves as a critical reference standard and a key synthetic intermediate in the study of mutagenic and carcinogenic processes. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical development companies engaged in environmental toxicology, metabolic pathway analysis, and the development of detection methodologies for complex hydrocarbons.

Application

• Analytical Reference Standard: Used as a certified reference material (CRM) for the calibration of analytical instruments like HPLC, GC-MS, and LC-MS in environmental and food safety testing.
• Biochemical Research: Serves as a substrate or metabolite analog in studies investigating the enzymatic activation (e.g., by cytochrome P450) and DNA adduct formation of polycyclic aromatic hydrocarbons.
• Toxicology Studies: Employed in in vitro and in vivo assays to assess the mutagenic and carcinogenic potential of PAH derivatives and their metabolic pathways.
• Pharmaceutical Development: Acts as a specialized synthetic intermediate or a molecular probe in the discovery and development of compounds targeting specific metabolic enzymes or DNA repair mechanisms.
• Environmental Monitoring: Used in method development and validation for the trace-level detection and quantification of complex PAH contaminants in soil, water, and air samples.

Basic Information

Product Name	12-N,n-Diacetylaminobenzo(A)Pyrene
CAS No.	82513-66-4
Molecular Formula	C28H21NO2
Molecular Weight	403.47 g/mol
Synonyms	12-(Diacetylamino)benzo[a]pyrene; N,N-Diacetyl-12-aminobenzo[a]pyrene; 12-Aminobenzo[a]pyrene N,N-diacetate; Benzo[a]pyrene-12-yl N,N-diacetamide; 12-Diacetamidobenzo(a)pyrene; B[a]P-12-N,N-diacetamide; 12-Acetamidobenzo[a]pyrene diacetate (mixture)
EINECS	Contact for details

Quality Control

Every batch of 12-N,n-Diacetylaminobenzo(A)Pyrene is manufactured under strict quality protocols and undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Our products are suitable for use as high-grade reference materials in sensitive research applications. Certificates of Analysis (COA) detailing results from HPLC, NMR, and MS are provided with each shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere at lower temperatures (-20°C).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.