Description

2-Methanesulfonyl-1H-Pyrrole is a versatile heterocyclic building block characterized by its reactive pyrrole core and methanesulfonyl protecting/activating group. This compound matters for its crucial role as a key intermediate in the synthesis of complex pharmaceutical molecules and advanced agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyrrole moiety contributes to biological activity.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing more complex N-heterocycles and functionalized organic molecules in laboratory and process chemistry.
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and other functional materials due to its electron-rich pyrrole structure.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors.

Basic Information

Product Name	2-Methanesulfonyl-1H-Pyrrole
CAS No.	82511-61-3
Molecular Formula	C5H7NO2S
Molecular Weight	145.18 g/mol
Synonyms	1H-Pyrrole-2-sulfonic acid, methyl ester; 2-(Methylsulfonyl)-1H-pyrrole; 2-Methanesulfonylpyrrole; Methyl 2-pyrrolylsulfonate; 2-(Methylsulfonyl)pyrrole; 2-Mesyl-1H-pyrrole; Pyrrole-2-methyl sulfone
EINECS	Contact for details

Quality Control

Our 2-Methanesulfonyl-1H-Pyrrole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.