Description

3-Iodo-Cinnoline is a halogenated heterocyclic organic compound serving as a versatile and high-value synthetic building block. Its core value lies in its iodine substituent, which enables efficient cross-coupling reactions for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of cinnoline-based drug candidates, including potential kinase inhibitors and anti-cancer agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with novel modes of action.
• Material Science: Serves as a building block for creating organic semiconductors, liquid crystals, and photoactive materials.
• Chemical Synthesis: Enables Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to introduce the cinnoline scaffold into more complex molecules.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.
• Ligand Synthesis: Can be utilized to prepare novel nitrogen-containing ligands for catalysis.

Basic Information

Product Name	3-Iodo-Cinnoline
CAS No.	82453-00-7
Molecular Formula	C8H5IN2
Molecular Weight	256.04 g/mol
Synonyms	3-Iodocinnoline; Cinnoline, 3-iodo-; 3-Iodo-1,2-diazanaphthalene; 3-Iodobenzodiazine; 82453-00-7 (CAS); 3-Iodocinoline; 3-Iodo-cinnolin
EINECS	Contact for details

Quality Control

Our 3-Iodo-Cinnoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.