Description

3-Iodo-4(1H)-Cinnolinone CAS NO 82452-98-0 is a high-purity, halogenated heterocyclic compound belonging to the cinnolinone class, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique iodine-substituted structure, which provides a versatile handle for cross-coupling reactions and further functionalization, enabling the construction of complex molecular architectures. This building block is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and exploring new chemical spaces in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a building block for creating specialized organic materials, such as ligands for catalysts or components for organic electronics.
• Chemical Biology: Employed as a probe or a tagged compound in biochemical assays and mechanism-of-action studies.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and heterocyclic chemistry at universities and CROs.

Basic Information

Item	Details
Product Name	3-Iodo-4(1H)-Cinnolinone
CAS No.	82452-98-0
Molecular Formula	C8H5IN2O
Molecular Weight	272.04 g/mol
Synonyms	3-Iodo-4-cinnolinone; 3-Iodo-4-hydroxycinnoline; 4-Hydroxy-3-iodocinnoline; 3-Iodocinnolin-4(1H)-one; 82452-98-0; 3-Iodo-1H-cinnolin-4-one
EINECS	Contact for details

Quality Control

Every batch of 3-Iodo-4(1H)-Cinnolinone is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.