Description

Benzo(A)Pyrenyl-7-Glucuronide is a crucial metabolite and analytical reference standard used in environmental and biological monitoring. This compound is essential for the accurate quantification and study of benzo(a)pyrene metabolism, a potent polycyclic aromatic hydrocarbon (PAH) carcinogen. It is primarily utilized by analytical laboratories, toxicology researchers, and environmental testing facilities for method development, calibration, and quality control in exposure assessment programs.

Application

• Biomarker Analysis: A critical reference standard for quantifying benzo(a)pyrene metabolites in human biological monitoring (e.g., urine, blood) to assess PAH exposure.
• Toxicology & Metabolic Studies: Used in in vitro and in vivo research to elucidate the Phase II conjugation pathways and detoxification mechanisms of benzo(a)pyrene.
• Environmental Monitoring: Serves as a calibration standard in analytical methods (HPLC, LC-MS/MS) for detecting PAH metabolites in environmental and occupational health samples.
• Method Development & Validation: Essential for developing, optimizing, and validating sensitive analytical protocols in accredited testing laboratories.
• Quality Control (QC) & Assurance (QA): Used as an internal or external standard to ensure the accuracy, precision, and reliability of analytical results in compliance-driven testing.
• Pharmacokinetic Research: Employed in studies investigating the absorption, distribution, metabolism, and excretion (ADME) of carcinogenic PAHs.

Basic Information

Product Name	Benzo(A)Pyrenyl-7-Glucuronide
CAS No.	82298-37-1
Molecular Formula	C26H24O8
Molecular Weight	464.47 g/mol
Synonyms	Benzo[a]pyren-7-yl-β-D-glucopyranosiduronic acid; 7-Hydroxybenzo[a]pyrene glucuronide; BP-7-Glucuronide; 7-BP-Gluc; Benzo(a)pyrene 7-O-β-D-glucuronide; B[a]P-7-Glucuronide; 7-(β-D-Glucopyranuronosyloxy)benzo[a]pyrene
EINECS	Contact for details

Quality Control

Every batch of Benzo(A)Pyrenyl-7-Glucuronide is manufactured and analyzed under strict quality management systems. Our products undergo rigorous identity, purity, and stability testing using advanced analytical techniques such as HPLC, LC-MS, and NMR to ensure compliance with research and analytical standards. A comprehensive Certificate of Analysis (COA), detailing batch-specific results, is provided and available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the material may be stored at 2-8°C. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation. The product is intended for laboratory use only by trained personnel.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.