Description

Xylosylphosphoryldolichol CAS NO 82249-54-5 is a key biochemical intermediate involved in the glycosylation pathway, specifically in the biosynthesis of N-linked glycoproteins. This compound is critical for research into protein processing, cellular signaling, and congenital disorders of glycosylation (CDG). It is primarily utilized by researchers and manufacturers in the fields of biochemistry, glycobiology, and pharmaceutical development for studying enzyme mechanisms and developing therapeutic targets.

Application

• Biochemical Research: Essential substrate for studying the enzymatic activity of dolichyl-phosphate β-D-xylosyltransferase and related glycosyltransferases.
• Glycobiology Studies: Used in in vitro assays to investigate the early steps of the N-linked oligosaccharide assembly pathway in the endoplasmic reticulum.
• Drug Discovery: Serves as a reference standard and tool compound for screening inhibitors targeting glycosylation disorders and certain viral replication cycles.
• Diagnostic Development: Potential use in developing assays for diagnosing congenital disorders of glycosylation (CDG).
• Enzyme Characterization: Employed to determine kinetic parameters and substrate specificity of enzymes involved in lipid-linked oligosaccharide synthesis.
• Academic & Industrial R&D: Fundamental reagent for universities, research institutes, and biotech companies exploring protein maturation and cell surface biology.

Basic Information

Product Name	Xylosylphosphoryldolichol
CAS No.	82249-54-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Dolichyl D-xylosyl phosphate; Dolichyl phosphate xylose; Dolichyl-P-Xyl; Xylose-dolichyl phosphate; P-D-Xylosyl-dolichol; Dolichol monophosphate xylose; Xylosylphosphodolichol; α-D-Xylosylphosphoryldolichol
EINECS	Contact for details

Quality Control

Our Xylosylphosphoryldolichol is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. All materials are characterized using advanced analytical techniques, including NMR and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. Due to its hygroscopic (moisture-sensitive) nature, containers must be sealed under an inert atmosphere after opening and allowed to equilibrate to room temperature before use to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in chloroform, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.