Description

(S)-(+)-2-(p-Toluenesulfinyl)-2-Cyclopentenoneethyleneketal is a high-value chiral building block and synthetic intermediate, distinguished by its sulfinyl group and protected ketone functionality. This compound matters for its critical role in facilitating asymmetric synthesis, enabling the production of enantiomerically pure molecules with high stereoselectivity. It is primarily needed by researchers and manufacturers in the pharmaceutical and fine chemical industries for developing advanced active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Asymmetric Synthesis: A key chiral auxiliary or ligand precursor for stereoselective carbon-carbon bond formation and other catalytic transformations.
• Pharmaceutical Intermediate: Used in the research and development of novel APIs, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Natural Product Synthesis: Serves as a versatile building block in the total synthesis of complex natural products with cyclopentane or cyclopentenone cores.
• Methodology Development: Employed by academic and industrial chemists to develop new synthetic methodologies involving sulfoxide chemistry.
• Agrochemical Research: Potential intermediate in the synthesis of chiral, biologically active compounds for crop protection.
• Material Science Precursor: Can be utilized in the synthesis of specialized organic materials and ligands for catalysis.

Basic Information

Product Name	(S)-(+)-2-(p-Toluenesulfinyl)-2-Cyclopentenoneethyleneketal
CAS No.	82136-15-0
Molecular Formula	C₁₄H₁₈O₃S
Molecular Weight	266.36 g/mol
Synonyms	(S)-(+)-2-(p-Tolylsulfinyl)-2-cyclopentenone ethylene ketal; (S)-2-[(4-Methylphenyl)sulfinyl]-2-cyclopentenone ethylene ketal; (S)-(+)-2-(4-Methylbenzenesulfinyl)-2-cyclopentenone ethylene ketal; (S)-2-(p-Toluenesulfinyl)-2-cyclopentenone ethylene ketal; (S)-2-(4-Methylphenylsulfinyl)-2-cyclopentenone ethylene ketal; (S)-2-(Tosyloxymethyl)-2-cyclopentenone ethylene ketal (related); 2-Cyclopentenone, 2-[(4-methylphenyl)sulfinyl]-, ethylene ketal, (S)-
EINECS	Contact for details

Quality Control

Our (S)-(+)-2-(p-Toluenesulfinyl)-2-Cyclopentenoneethyleneketal is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee batch-to-batch consistency and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.