Description

3-(4-Chloro-Phenyl)-3-Hydroxy-2-Methyl-1-Phenyl-Propan-1-One is a high-purity organic intermediate characterized by its chiral β-hydroxy ketone structure. This compound is valued for its role as a versatile building block in the synthesis of complex, biologically active molecules, offering critical stereochemical control. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its specific stereochemistry can influence biological activity.
• Asymmetric Catalysis Research: Serves as a standard substrate or ligand precursor in academic and industrial research focused on novel catalytic processes.
• Fine Chemical Production: Employed in the multi-step synthesis of other specialty chemicals, flavors, and fragrances requiring precise molecular architecture.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing polymers with specific optical or mechanical properties.

Basic Information

Product Name	3-(4-Chloro-Phenyl)-3-Hydroxy-2-Methyl-1-Phenyl-Propan-1-One
CAS No.	82105-36-0
Molecular Formula	C₁₆H₁₅ClO₂
Molecular Weight	274.74 g/mol
Synonyms	1-Propanone, 3-(4-chlorophenyl)-3-hydroxy-2-methyl-1-phenyl-; 3-Hydroxy-3-(4-chlorophenyl)-2-methyl-1-phenylpropan-1-one; 4'-Chloro-2-methylbenzoin; (RS)-3-(4-Chlorophenyl)-3-hydroxy-2-methyl-1-phenylpropan-1-one; (±)-3-(4-Chlorophenyl)-3-hydroxy-2-methylpropiophenone; Benzoin, 4'-chloro-2-methyl-; α-Methyl-4-chlorobenzoylbenzyl alcohol
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Chloro-Phenyl)-3-Hydroxy-2-Methyl-1-Phenyl-Propan-1-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, chiral purity (if applicable), and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.