Description

Benzene, [14C(U)] CAS NO 82049-87-4 is a uniformly carbon-14 labeled isotopologue of benzene, a fundamental aromatic hydrocarbon. This radiolabeled compound is an indispensable tool for tracing metabolic pathways, studying environmental fate, and conducting advanced pharmacokinetic research. It is primarily required by pharmaceutical R&D laboratories, agrochemical developers, and environmental scientists for precise, high-sensitivity tracer studies.

Application

• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used as a tracer to elucidate the absorption, distribution, metabolism, and excretion (ADME) profiles of new chemical entities in preclinical research.
• Environmental Fate and Biodegradation Research: Employed to track the breakdown pathways, persistence, and transformation products of benzene and related compounds in ecosystems.
• Biochemical Pathway Analysis: Serves as a labeled precursor in studying aromatic compound metabolism in microorganisms, plants, and mammalian systems.
• Agrochemical Research: Utilized in the development and environmental safety assessment of pesticides and herbicides to understand their degradation and mobility.
• Chemical Synthesis Tracing: Acts as a labeled building block in the synthesis of more complex 14C-labeled compounds for various research applications.
• Toxicological Studies: Applied to investigate the mechanisms of benzene toxicity and its metabolic activation in biological models.

Basic Information

Product Name	Benzene, [14C(U)]
CAS No.	82049-87-4
Molecular Formula	C6[14C]6H6
Molecular Weight	84.09 (average, based on 100% 14C enrichment)
Synonyms	[14C]Benzene; Uniformly Labeled [14C]Benzene; Benzene-14C(U); Carbon-14 Labeled Benzene; Radiolabeled Benzene; 14C-Benzene; Benzene (14C); Cyclohexatriene-14C(U)
EINECS	Contact for details

Quality Control

Every batch of Benzene, [14C(U)] is produced and analyzed under strict quality control protocols to ensure the highest standards of radiochemical purity, chemical purity, and specific activity. Our products undergo rigorous quality testing, including HPLC and radio-HPLC analysis, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing specific activity, radiochemical purity, and analytical methods are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a dedicated, well-ventilated area for radioactive materials. Due to its highly volatile nature, ensure containers are securely sealed. Follow all local and international regulations for the storage and handling of radioactive substances.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 98%
Chemical Purity (GC)	≥ 99%
Specific Activity	Customizable (mCi/mmol range)
Solvent	Toluene or other suitable solvent (as specified)
Concentration	As per customer requirement

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.