Description

4α-Hydroxyadamantane-1-Carboxylic Acid is a high-purity, functionalized adamantane derivative that serves as a critical building block in advanced organic synthesis. Its unique rigid, cage-like structure combined with both carboxylic acid and hydroxyl functionalities makes it a versatile intermediate for creating complex molecular architectures with enhanced properties. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and specialty chemical sectors seeking to develop novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies, leveraging the adamantane scaffold's metabolic stability and lipophilicity.
• Advanced Material Synthesis: Used to create monomers and cross-linkers for high-performance polymers, resins, and coatings with improved thermal stability and mechanical strength.
• Ligand and Catalyst Development: Serves as a backbone for designing sophisticated chelating ligands and organocatalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Agrochemical Research: Employed in developing new generation crop protection agents with novel modes of action and enhanced environmental profiles.
• Dendrimer and Macromolecule Construction: The multiple functionalization sites make it an ideal core or branching unit for constructing complex dendritic structures.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and protein interactions.

Basic Information

Item	Detail
Product Name	4α-Hydroxyadamantane-1-Carboxylic Acid
CAS No.	81968-77-6
Molecular Formula	C11H16O3
Molecular Weight	196.24 g/mol
Synonyms	4-Hydroxyadamantane-1-carboxylic acid; 1-Adamantanecarboxylic acid, 4-hydroxy-; 4-Hydroxy-1-adamantanecarboxylic acid; 4-Hydroxytricyclo[3.3.1.13,7]decane-1-carboxylic acid; 4-Hydroxyadamantane-1-carboxylate; 4-HO-Ada-1-COOH; 4-Hydroxy-1-carboxyadamantane
EINECS	Contact for details

Quality Control

Every batch of 4α-Hydroxyadamantane-1-Carboxylic Acid is manufactured under strict quality management protocols. We employ advanced analytical techniques, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, and we support compliance with relevant regulatory frameworks for target industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.