Description

4-Hydroxy-7-Bromo-1-Indanone is a specialized brominated indanone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated hydroxyindanone structure makes it a valuable building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the indanone scaffold's bioactivity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its halogenated structure.
• Material Science Research: Serves as a monomer or building block for the development of organic electronic materials, such as OLEDs or conductive polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Industrial R&D: A versatile starting material for methodological studies in organic synthesis, including cross-coupling reactions and heterocycle formation.
• Fine Chemical Production: Used in the custom synthesis of complex, high-value specialty chemicals for various technological applications.

Basic Information

Product Name	4-Hydroxy-7-Bromo-1-Indanone
CAS No.	81945-21-3
Molecular Formula	C9H7BrO2
Molecular Weight	227.06 g/mol
Synonyms	7-Bromo-4-hydroxy-1-indanone; 4-Hydroxy-7-bromoindan-1-one; 1-Indanone, 4-hydroxy-7-bromo-; 7-Bromo-4-hydroxyindan-1-one; 81945-21-3; 4-Hydroxy-7-bromo-2,3-dihydro-1H-inden-1-one
EINECS	Contact for details

Quality Control

Every batch of 4-Hydroxy-7-Bromo-1-Indanone is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard quality protocol includes HPLC for assay determination and impurity profiling, supported by spectroscopic confirmation (IR, NMR). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all tested parameters. For custom synthesis or specific project requirements, we can tailor purity specifications and analytical methods in alignment with cGMP or other relevant quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.