Description

tert-Butyl 7-Chloro-4-Oxo-3,4-Dihydroquinoline-1(2H)-Carboxylate is a high-purity, protected heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents and fine chemicals, offering a versatile scaffold for further functionalization. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinoline-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Research: Used in the development of new herbicides and fungicides that leverage the bioactive quinoline core.
• Organic Synthesis Building Block: The tert-butyloxycarbonyl (Boc) protecting group allows for selective reactions, making it valuable for multi-step synthetic routes in medicinal chemistry.
• Material Science Research: Investigated as a monomer or precursor for creating novel organic electronic materials and functional polymers.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	tert-Butyl 7-Chloro-4-Oxo-3,4-Dihydroquinoline-1(2H)-Carboxylate
CAS No.	81892-54-8
Molecular Formula	C₁₄H₁₄ClNO₃
Molecular Weight	279.72 g/mol
Synonyms	1-Boc-7-chloro-1,2-dihydro-4-oxoquinoline; 7-Chloro-1,2-dihydro-4-oxoquinoline-1-carboxylic acid tert-butyl ester; tert-Butyl 7-chloro-1,2-dihydro-4-oxo-1-quinolinecarboxylate; 1-(tert-Butoxycarbonyl)-7-chloro-1,2-dihydro-4(3H)-quinolinone; 7-Chloro-4-oxo-1,2,3,4-tetrahydroquinoline-1-carboxylic acid tert-butyl ester; Boc-7-chloro-1,2-dihydro-4-oxoquinoline
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Chloro-4-Oxo-3,4-Dihydroquinoline-1(2H)-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.