Description

α-D-Galactofuranosyl Nitromethane is a specialized carbohydrate derivative and synthetic building block of significant interest in advanced organic and medicinal chemistry. Its unique galactofuranosyl structure linked to a nitromethane moiety makes it a valuable precursor for the synthesis of complex glycoconjugates and nucleoside analogs. This compound is primarily utilized by research institutions and pharmaceutical development teams working on novel therapeutic agents, diagnostic probes, and biochemical tools.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel antibiotics, antivirals, and other bioactive molecules targeting carbohydrate-processing enzymes.
• Glycochemistry Research: Used as a building block for the chemical and enzymatic synthesis of complex oligosaccharides and glycoconjugates containing the galactofuranose motif, which is rare in mammals but present in pathogens.
• Probe and Diagnostic Development: Acts as a precursor for labeled compounds (e.g., fluorescent or radiolabeled probes) used in studying galactofuranose metabolism in microorganisms like mycobacteria and fungi.
• Nucleoside Analog Synthesis: Employed in the creation of modified nucleosides for potential use as antimetabolites or tools in molecular biology.
• Enzyme Inhibitor Studies: Useful for designing and testing inhibitors of enzymes that recognize or process galactofuranose residues, such as certain galactofuranosidases.
• Bioconjugation Chemistry: The reactive nitromethane group can be leveraged for click chemistry or other bioconjugation strategies to attach sugars to proteins, surfaces, or other molecules.

Basic Information

Product Name	α-D-Galactofuranosyl Nitromethane
CAS No.	81812-46-6
Molecular Formula	C7H13NO7
Molecular Weight	223.18 g/mol
Synonyms	1-Deoxy-1-nitro-α-D-galactofuranose; α-D-Galactofuranosylnitromethane; Nitromethyl α-D-galactofuranoside; 1-Nitro-1-deoxy-α-D-galactofuranose; α-D-Galactofuranose-1-C-nitromethane; (2R,3S,4S,5R)-2-(Hydroxymethyl)-5-nitroxytetrahydrofuran-3,4-diol (related); Galactofuranose nitromethane derivative
EINECS	Contact for details

Quality Control

Our α-D-Galactofuranosyl Nitromethane is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.