Description

Ethyl 2 - (2 - Oxo - 3,4 - Dihydroquinolin - 1(2H) - Yl)Acetate is a high-purity synthetic intermediate of significant importance in advanced organic synthesis. This compound matters as a versatile building block for constructing complex heterocyclic frameworks, enabling the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinoline-based drug candidates, including potential kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides that leverage the quinolinone scaffold for biological activity.
• Fine Chemical Production: Serves as a crucial building block for creating complex molecules used in material science, dyes, and functional materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.
• Process Chemistry & Scale-Up: Utilized in optimizing synthetic routes from milligram to kilogram scale for commercial production.

Basic Information

Product Name	Ethyl 2 - (2 - Oxo - 3,4 - Dihydroquinolin - 1(2H) - Yl)Acetate
CAS No.	81745-20-2
Molecular Formula	C₁₃H₁₅NO₃
Molecular Weight	233.26 g/mol
Synonyms	Ethyl (2-oxo-1,2,3,4-tetrahydroquinolin-1-yl)acetate; 1-Acetic acid, 2-oxo-1,2,3,4-tetrahydroquinoline-, ethyl ester; Ethyl 2-(2-oxo-3,4-dihydro-1(2H)-quinolinyl)acetate; Ethyl (2-oxo-1,2,3,4-tetrahydroquinolin-1-yl)ethanoate; 1-Carbethoxymethyl-2-oxo-1,2,3,4-tetrahydroquinoline; 81745-20-2; Quinolinone derivative ester.
EINECS	Contact for details

Quality Control

Our Ethyl 2 - (2 - Oxo - 3,4 - Dihydroquinolin - 1(2H) - Yl)Acetate is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, from research to cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.