Description

1,3-Dioxolane-2-Ethanol, -α--Ethynyl-2-Methyl- CAS NO 81617-51-8 is a specialized organic compound featuring a dioxolane ring and an ethynyl group, making it a valuable chiral building block and intermediate in advanced synthetic chemistry. Its unique structure provides a versatile platform for constructing complex molecular architectures, particularly in the synthesis of pharmaceuticals and fine chemicals. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific functional groups and stereocenters into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for introducing the dioxolane moiety.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, including flavors, fragrances, and advanced polymers.
• Material Science Research: Employed in the development of novel organic frameworks and functional materials due to its reactive ethynyl group.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	1,3-Dioxolane-2-Ethanol, -α--Ethynyl-2-Methyl-
CAS No.	81617-51-8
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	2-(Ethynyl)-2-methyl-1,3-dioxolane-4-ethanol; α-Ethynyl-2-methyl-1,3-dioxolane-2-ethanol; 4-(2-Hydroxyethyl)-2-methyl-2-ethynyl-1,3-dioxolane; (4R)-2-Methyl-2-ethynyl-4-(2-hydroxyethyl)-1,3-dioxolane (for specific enantiomer); Ethynyl methyl dioxolane ethanol; Chiral dioxolane ethynyl intermediate
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-2-Ethanol, -α--Ethynyl-2-Methyl- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess (if applicable), and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage under an inert atmosphere (e.g., nitrogen or argon), please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (if applicable)	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.