Description

Ethyl 1-Ethyl-6-Fluoro-7-(4-Methylpiperazin-1-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of modern fluoroquinolone antibiotics, valued for its precise chemical structure and reactivity. It is essential for research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the development and production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluoroquinolone antibiotic APIs.
• Antibacterial Research: Used in medicinal chemistry for the research and development of new antibacterial agents with improved efficacy.
• Process Chemistry: Employed in scale-up and optimization studies for commercial pharmaceutical manufacturing.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory submissions.
• Custom Synthesis: A starting material for the custom synthesis of structurally related quinoline derivatives for biological screening.

Basic Information

Item	Details
Product Name	Ethyl 1-Ethyl-6-Fluoro-7-(4-Methylpiperazin-1-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate
CAS No.	81530-83-8
Molecular Formula	C19H24FN3O3
Molecular Weight	361.41 g/mol
Synonyms	1-Ethyl-6-fluoro-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid ethyl ester; Ethyl 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate; 7-(4-Methylpiperazin-1-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester; Intermediate for Gatifloxacin; Gatifloxacin intermediate; GTFX intermediate
EINECS	Contact for details

Quality Control

Our Ethyl 1-Ethyl-6-Fluoro-7-(4-Methylpiperazin-1-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.