Description

1-(3-Piperidinylmethyl)Piperidine Dihydrochloride is a high-purity organic salt compound, serving as a critical building block and intermediate in advanced pharmaceutical synthesis and fine chemical research. Its value lies in its functionalized piperidine scaffold, which is a privileged structure in medicinal chemistry for modulating biological activity. This product is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and life science industries who require reliable, high-quality intermediates for API development and scale-up.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and library synthesis for drug discovery programs focusing on GPCRs and other central nervous system targets.
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents and pesticides.
• Chemical Biology Probes: Serves as a precursor for developing tool compounds and molecular probes used in biochemical and pharmacological studies.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing of complex, high-value specialty chemicals.

Basic Information

Product Name	1-(3-Piperidinylmethyl)Piperidine Dihydrochloride
CAS No.	81310-57-8
Molecular Formula	C11H22N2·2HCl
Molecular Weight	251.22 g/mol (Free base: 182.31 g/mol)
Synonyms	1-[(Piperidin-3-yl)methyl]piperidine dihydrochloride; 3-(Piperidin-1-ylmethyl)piperidine dihydrochloride; 1,1'-(Piperidine-3,1-diyl)dimethanediyl)dipiperidine dihydrochloride (mixture isomer); Bis(piperidinylmethyl)amine dihydrochloride (related); Piperidine, 1,1'-(1,3-propanediyl)bis-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-Piperidinylmethyl)Piperidine Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and other relevant spectroscopic methods. Our quality standards are designed to meet the rigorous demands of cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture from the air, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.